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A0364656

LinoleicAcid,watersoluble

Synonym(s):
Linoleic acid;Linoleic Acid - CAS 60-33-3 - Calbiochem;Linolic Acid, cis,cis-9,12-Octadecadienoic Acid;Telfairic acid;cis,cis-9,12-Octadecadienoic Acid, Linolic Acid

CAS NO.:

Empirical Formula: C18H32O2

Molecular Weight: 280.45

MDL number: MFCD00064241

EINECS: 200-470-9

Pack Size Price Stock Quantity
10mg RMB173.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: -5 °C (lit.)
Boiling point: 229-230 °C/16 mmHg (lit.)
Density  0.902 g/mL at 25 °C (lit.)
FEMA  3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%)
refractive index  n20/D 1.466(lit.)
Flash point: >230 °F
storage temp.  Store below +30°C.
solubility  NaOH: soluble1M
pka 4.77(at 25℃)
form  liquid
color  Clear yellow
Odor faint fatty
Water Solubility  INSOLUBLE
FreezingPoint  -5℃
Sensitive  Air Sensitive
λmax 270nm(H2O)(lit.)
JECFA Number 332
Merck  14,5505
BRN  1727101
Dielectric constant 2.6(0℃)
Stability: Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKey OYHQOLUKZRVURQ-KQHSAVHASA-N
LogP 7.050

Description and Uses

Linoleic acid is an essential ω-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 μM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay. Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.

Unsaturated μ-6 fatty acid Linoleic acid is involved in the production of quick-drying oils which are used in oil paints and varnishes. It is also used in beauty products due to its beneficial properties on the skin such as moisture retention. It is a key starting material for the synthesis of linoleyl alcohol and octadecanoic acid. It is used as a precursor of arachidonic acid (AA) and various prostaglandins. It may be used to improve the delivery and efficacy of anti-cancer drugs and in cancer protection.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P305+P351+P338-P370+P378-P403+P235
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  26-24/25-36-37/39
RIDADR  UN1170 - class 3 - PG 2 - Ethanol
WGK Germany  1
RTECS  RF9990000
8-10-23
TSCA  Yes
HS Code  29161500
Toxicity LD50 oral in mouse: > 50gm/kg

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