O-(2-Aminoethyl)-O′-[2-(Boc-amino)ethyl]octaethylene glycol , 97% , 890091-43-7

CAS NO.：890091-43-7

Empirical Formula: C25H52N2O11

Molecular Weight: 556.69

MDL number: MFCD03453249

PRODUCT Properties

• Boiling point: 609.8±55.0 °C(Predicted)
• Density: 1.082±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Soluble in Water, DMSO, DMF, DCM
• form: Liquid
• pka: 12.23±0.46(Predicted)
• color: Colorless to light yellow
• InChI: InChI=1S/C25H52N2O11/c1-25(2,3)38-24(28)27-5-7-30-9-11-32-13-15-34-17-19-36-21-23-37-22-20-35-18-16-33-14-12-31-10-8-29-6-4-26/h4-23,26H2,1-3H3,(H,27,28)
• InChIKey: RTTGVFBQUXJWJG-UHFFFAOYSA-N
• SMILES: C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Description and Uses

t-Boc-N-amido-PEG9-amine is a monodisperse PEG reagent containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• WGK Germany: 3
• HS Code: 2924190090