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A1240512

Baicalein , 98% , 491-67-8

Synonym(s):
5,6,7-Trihydroxyflavone;Baicalein - CAS 491-67-8 - Calbiochem

CAS NO.:491-67-8

Empirical Formula: C15H10O5

Molecular Weight: 270.24

MDL number: MFCD00017459

EINECS: 000-000-0

Pack Size Price Stock Quantity
100MG RMB37.60 In Stock
1G RMB70.40 In Stock
5G RMB110.40 In Stock
25G RMB380.00 In Stock
100G RMB1380.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 256-271 °C (lit.)
Boiling point: 373.35°C (rough estimate)
Density  1.3280 (rough estimate)
refractive index  1.5000 (estimate)
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Yellow solid
pka 6.31±0.40(Predicted)
color  Yellow or yellow-green
Merck  14,942
BRN  272683
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChIKey FXNFHKRTJBSTCS-UHFFFAOYSA-N
LogP 3.310 (est)

Description and Uses

Baicalein (491-67-8) is an inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis.1?Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64 μM for 12-LO and 1.6 μM for 15-LO).2 Baicalein displays anti-inflammatory activity and inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (IC50=36 μM).3

An inhibitor of Ca2+ uptake, 5-LO, and 12-LO

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  DJ3100898
Hazard Note  Irritant
HS Code  29329990

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