A1396512
3-Bromo-4-chloroaniline , >98.0%(GC) , 823-54-1
| Pack Size | Price | Stock | Quantity |
| 1G | RMB24.00 | In Stock |
|
| 250MG | RMB41.04 | In Stock |
|
| 5G | RMB95.04 | In Stock |
|
| 25g | RMB221.60 | In Stock |
|
| 100g | RMB415.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 82°C |
| Boiling point: | 290.6±20.0℃ (760 Torr) |
| Density | 1.722±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 129.5±21.8℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 2.89±0.10(Predicted) |
| color | White to Brown |
Description and Uses
3-Bromo-4-chloroaniline can be used as an intermediate in pharmaceutical synthesis, such as the preparation of Vismodegib, the trade name is Erivedge, the chemical name is 2-chloro-N-(4-chloro-3 -(Pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, developed by Curis, Genentech and Evotec in cooperation, was approved by the U.S. Food and Drug Administration (FDA) on January 30, 2012 ) marketing approval as a small molecule targeted inhibitor of the Hedgehog pathway for the treatment of basal cell carcinoma.
3-Bromo-4-chloroaniline is an amine derivative and can be used as an organic reagent.
Safety
| Symbol(GHS) |    GHS07,GHS06,GHS08 |
| Signal word | Warning |
| Hazard statements | H302-H312-H331-H373-H302+H312+H332-H315-H319 |
| Precautionary statements | P260-P280h-P304+P340-P311a-P405-P501a-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 |
| Risk Statements | 20/21/22-33 |
| Safety Statements | 36/37 |
| RIDADR | 2811 |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 29214200 |
