Home Categories D-Lin-MC3-DMA
A2611851

D-Lin-MC3-DMA , 98% , 1224606-06-7

CAS NO.:1224606-06-7

Empirical Formula: C43H79NO2

Molecular Weight: 642.09

MDL number: MFCD31657426

Pack Size Price Stock Quantity
1mg RMB239.20 In Stock
5mg RMB559.20 In Stock
10mg RMB1039.20 In Stock
25mg RMB1599.20 In Stock
50mg RMB2399.20 In Stock
100mg RMB3999.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 670.2±43.0 °C(Predicted)
Density  0.886±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  Soluble in Ethanol, DMSO, DMF
pka 9.37±0.28(Predicted)
form  Liquid
color  Colorless to light yellow
InChIKey NRLNQCOGCKAESA-KWXKLSQISA-N
SMILES C(OC(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC)(=O)CCCN(C)C

Description and Uses

D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is a potent and ionizable cationic lipid. D-Lin-MC3-DMA is used for delivery of siRNA in vivo. DLin-MC3-DMA, or (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate , is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.

DLin-M-C3-DMA is a commonly used drug delivery vehicle for the fabrication of lipid nanoparticles (LNPs), which exert therapeutic effects by encapsulating and delivering siRNA, mRNA, DNA, or small molecules into the cytoplasm of the cell, and is a potent siRNA delivery vehicle.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

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