Ethyl bromoacetate , 98% , 105-36-2
Synonym(s):
Bromoacetic acid ethyl ester;Ethyl bromoacetate
CAS NO.：105-36-2
Empirical Formula: C4H7BrO2
Molecular Weight: 167
MDL number: MFCD00000191
EINECS: 203-290-9
PRODUCT Properties
| Melting point: | -38 °C |
| Boiling point: | 159 °C(lit.) |
| Density | 1.506 g/mL at 25 °C(lit.) |
| vapor density | 5.8 (vs air) |
| vapor pressure | 2.6 mm Hg ( 25 °C) |
| refractive index | n |
| Flash point: | 118 °F |
| storage temp. | Store below +30°C. |
| solubility | water: insoluble |
| form | Liquid |
| Specific Gravity | 1.506 |
| color | Clear |
| Odor | Pungent odour |
| Water Solubility | Miscible with ethanol, acetone, benzene and ethyl ether. Immiscible with water. |
| BRN | 506456 |
| Dielectric constant | 9.75 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, water, strong acids. |
| InChIKey | PQJJJMRNHATNKG-UHFFFAOYSA-N |
Description and Uses
Ethyl bromoacetate is a clear, colorless tolight-yellow liquid. Molecular weight = 167.02; Boilingpoint = 159℃. Freezing point ≤－20℃; Flashpoint = 48℃. Hazard Identification (based on NFPA-704 MRating System): Health 2, Flammability 2, Reactivity 0.Insoluble in water
Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.
Safety
| Symbol(GHS) |   GHS02,GHS06 |
| Signal word | Danger |
| Hazard statements | H226-H300+H310+H330 |
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P304+P340+P310 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 26-45-7/9-1/2 |
| RIDADR | UN 1603 6.1/PG 2 |
| WGK Germany | 1 |
| RTECS | AF6000000 |
| F | 19 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29159080 |
