(S)-(+)-N-(2,3-Epoxypropyl)phthalimide , >98.0%(GC) , 161596-47-0

Synonym(s):
(S)-N-Glycidylphthalimide

CAS NO.：161596-47-0

Empirical Formula: C11H9NO3

Molecular Weight: 203.19

MDL number: MFCD04973350

EINECS: 1308068-626-2

PRODUCT Properties

• Melting point: 102 °C
• Boiling point: 347.4±15.0 °C(Predicted)
• Density: 1.446±0.06 g/cm3(Predicted)
• vapor pressure: 0.001-2.17Pa at 25-90.25℃
• refractive index: 10 ° (C=2.2, CHCl3)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• pka: -2.24±0.20(Predicted)
• form: Solid
• color: White
• optical activity: Consistent with structure
• InChI: InChI=1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1
• InChIKey: DUILGEYLVHGSEE-ZETCQYMHSA-N
• SMILES: C1(=O)C2=C(C=CC=C2)C(=O)N1C[C@H]1CO1
• LogP: 1.2 at 40℃

Description and Uses

(S)-(+)-Glycidyl Phthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500). It is also a key intermediate of rivaroxaban.

Safety

• Symbol(GHS): GHS05,GHS08
• Signal word: Danger
• Hazard statements: H318-H341
• Precautionary statements: P201-P202-P305+P351+P338+P310-P308+P313-P405-P501-P280-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 41
• Safety Statements: 26-39
• WGK Germany: 2
• HS Code: 29252900