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A4285712

Folic acid , USP level , 59-30-3

Synonym(s):
Folic acid;Cyanocobalamin;Vitamin M;Pteroylglutamic acid;Pterylmonoglutamic acid

CAS NO.:59-30-3

Empirical Formula: C19H19N7O6

Molecular Weight: 441.4

MDL number: MFCD00079305

EINECS: 200-419-0

Pack Size Price Stock Quantity
25G RMB239.20 In Stock
100G RMB799.20 In Stock
500g RMB2799.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 250 °C
Boiling point: 552.35°C (rough estimate)
alpha  20 º (c=1, 0.1N NaOH)
Density  1.4704 (rough estimate)
refractive index  1.6800 (estimate)
storage temp.  2-8°C
solubility  boiling water: soluble1%
form  Crystalline Powder
pka pKa 2.5 (Uncertain)
color  Yellow to orange
Odor Odorless
PH Range 4
Water Solubility  1.6 mg/L (25 ºC)
Merck  14,4221
BRN  100781
BCS Class 3
Stability: Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.
InChIKey OVBPIULPVIDEAO-LBPRGKRZSA-N
LogP -0.990 (est)

Description and Uses

Folic acid is an essential B vitamin. It is converted to folate in vivo, which is a necessary cofactor for a variety of biological processes, including nucleotide synthesis and, thus, DNA synthesis and repair, among others. A deficiency in dietary folic acid can lead to a range of developmental and cognitive disorders, most prominently neural tube defects and congenital heart defects.

folic acid is generally used as an emollient. In vitro and in vivo skin studies now indicate its capacity to aid in DnA synthesis and repair, promote cellular turnover, reduce wrinkles, and promote skin firmness. There is some indication that folic acid may also protect DnA from uV-induced damage. Folic acid is a member of the vitamin B complex and is naturally occurring in leafy greens.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  33-62-68
Safety Statements  24/25
WGK Germany  1
RTECS  LP5425000
8
TSCA  Yes
HS Code  29362900
Toxicity A water soluble vitamin required in the diet of mammals. Sulfonamide drugs are selectively toxic to bacteria because they inhibit the incorporation of p-aminobenzoic acid into folic acid, a biosynthetic process in bacteria. Folic acid deficiency adversely affects prenatal development in humans. Dietary supplementation with folic acid dramatically reduces the incidence of neural tube defects in humans. Folic acid deficiency may also contribute to the causes of megaloblastic macrocytic anemia and a consequence of this is that this disease can be induced, as a side effect, when methotrexate, a folic acid antagonist, is used in cancer chemotherapy

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