A4722612
trans-4-Hydroxy-L-proline , 99% , 51-35-4
Synonym(s):
Hyp;Hydroxyproline;4-Hydroxyproline;L(-)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp;(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid
CAS NO.:51-35-4
Empirical Formula: C5H9NO3
Molecular Weight: 131.13
MDL number: MFCD00064320
EINECS: 200-091-9
| Pack Size | Price | Stock | Quantity |
| 5G | RMB23.20 | In Stock |
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| 10g | RMB31.20 | In Stock |
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| 25G | RMB35.20 | In Stock |
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| 100G | RMB86.40 | In Stock |
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| 250g | RMB197.60 | In Stock |
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| 500G | RMB318.40 | In Stock |
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| 2.5kg | RMB1380.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 273 °C (dec.)(lit.) |
| alpha | -75.5 º (c=5, H2O) |
| Boiling point: | 242.42°C (rough estimate) |
| Density | 1.3121 (rough estimate) |
| bulk density | 610kg/m3 |
| vapor density | 4.5 (vs air) |
| refractive index | -75.5 ° (C=4, H2O) |
| storage temp. | Store below +30°C. |
| solubility | H2O: 50 mg/mL |
| form | Crystals or Crystalline Powder |
| pka | 1.82, 9.66(at 25℃) |
| color | White |
| Odor | Odorless |
| PH | 5.5-6.5 (50g/l, H2O, 20℃) |
| optical activity | [α]25/D 75.6°, c = 1 in H2O |
| Water Solubility | 357.8 g/L (20 º C) |
| Merck | 14,4840 |
| BRN | 471933 |
| InChIKey | PMMYEEVYMWASQN-DMTCNVIQSA-N |
| LogP | -0.350 (est) |
| CAS DataBase Reference | 51-35-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Hydroxyproline(51-35-4) |
| EPA Substance Registry System | trans-4-Hydroxy-L-proline (51-35-4) |
Description and Uses
A non-essential amino acid. Can be isolated from gelatin. Hydroxyproline has not been reported as added to food in any of the NAS surveys.
A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.
Safety
| Symbol(GHS) | ![]() GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 24/25-36/37/39-27-26 |
| WGK Germany | 3 |
| RTECS | TW3586500 |
| TSCA | Yes |
| HazardClass | IRRITANT |
| HS Code | 29339990 |






