A4807512
4-Hydroxy-1-methylpiperidine , >98.0%(GC) , 106-52-5
Synonym(s):
1-Methyl-4-piperidinol;4-Hydroxy-1-methylpiperidine
CAS NO.：106-52-5
Empirical Formula: C6H13NO
Molecular Weight: 115.17
MDL number: MFCD00006500
EINECS: 203-406-8
| Pack Size | Price | Stock | Quantity |
| 25G | RMB30.40 | In Stock |
|
| 100G | RMB77.60 | In Stock |
|
| 500G | RMB362.40 | In Stock |
|
| 1kg | RMB660.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 29-31 °C(lit.) |
| Boiling point: | 200 °C(lit.) |
| Density | 0.98 g/mL at 20 °C(lit.) |
| vapor pressure | 8.13-11Pa at 25℃ |
| refractive index | n |
| Flash point: | 190 °F |
| storage temp. | 2-8°C |
| form | Liquid After Melting |
| pka | 14.87±0.20(Predicted) |
| color | Clear colorless to brown |
| Water Solubility | MISCIBLE |
| Sensitive | Hygroscopic |
| BRN | 103024 |
| LogP | -0.14-0.756 at 25℃ |
| CAS DataBase Reference | 106-52-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Hydroxy-N-methylpiperidine(106-52-5) |
| EPA Substance Registry System | 4-Piperidinol, 1-methyl- (106-52-5) |
Description and Uses
4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H315-H318-H335 |
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | Xi,C |
| Risk Statements | 37/38-41-36/37/38-34 |
| Safety Statements | 26-37/39-45-36/37/39-27 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29333999 |
