6-Methylnicotinic Acid , 99% , 3222-47-7
Synonym(s):
6-Methylnicotinic acid;6-Methylpyridine-3-carboxylic acid
CAS NO.：3222-47-7
Empirical Formula: C7H7NO2
Molecular Weight: 137.14
MDL number: MFCD00006341
EINECS: 670-942-0
| Pack Size | Price | Stock | Quantity |
| 1G | RMB25.60 | In Stock |
|
| 5G | RMB38.40 | In Stock |
|
| 25G | RMB116.00 | In Stock |
|
| 100G | RMB463.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 210-213 °C (lit.) |
| Boiling point: | 251.96°C (rough estimate) |
| Density | 1.2528 (rough estimate) |
| refractive index | 1.5030 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder, Crystals and/or Chunks |
| pka | 2.37±0.10(Predicted) |
| color | White to light yellow to beige |
| Water Solubility | Sparingly soluble in water. |
| BRN | 112049 |
| InChI | InChI=1S/C7H7NO2/c1-5-2-3-6(4-8-5)7(9)10/h2-4H,1H3,(H,9,10) |
| InChIKey | RZOKQIPOABEQAM-UHFFFAOYSA-N |
| SMILES | C1=NC(C)=CC=C1C(O)=O |
| CAS DataBase Reference | 3222-47-7(CAS DataBase Reference) |
Description and Uses
6-Methylnicotinic acid is a biochemical reagent that can be used as a pharmaceutical intermediate or raw material for organic synthesis. 6-Methylnicotinic acid is used as the starting material and 6-methylnicotine can be synthesized through four steps of esterification, condensation, ring-opening rearrangement, and reduction. As an alkaloid, 6-methylnicotine has similarities with nicotine, but slight changes in its molecular structure may lead to differences in its pharmacological effects and addictiveness. It may be used in products such as electronic cigarettes as a substitute or supplement for nicotine.
6-Methylnicotinic acid is an intermediate of the drug etoricoxib (a non- steroidal anti-inflammatory drug for the treatment of arthritis and osteoarthritis). It is also used as organic intermediates.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 37/39-26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29333990 |
