A5527412
Mildronate dihydrate , ≥98% , 86426-17-7
Synonym(s):
MET 88;Quaterin
CAS NO.：86426-17-7
Empirical Formula: C6H14N2O2.2H2O
Molecular Weight: 182.218
MDL number: MFCD00876389
EINECS: 695-494-3
| Pack Size | Price | Stock | Quantity |
| 50MG | RMB37.60 | In Stock |
|
| 250MG | RMB79.20 | In Stock |
|
| 10g | RMB148.80 | In Stock |
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| 25g | RMB224.80 | In Stock |
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| 5g | RMB319.20 | In Stock |
|
| 100g | RMB561.60 | In Stock |
|
| 500g | RMB1684.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 85 - 87°C |
| storage temp. | 2-8°C |
| solubility | H2O: >40mg/mL |
| form | powder |
| color | white to off-white |
| Water Solubility | H2O: >40mg/mL |
| Stability: | Hygroscopic |
| InChIKey | JFWLFLLRLZSBRA-UHFFFAOYSA-N |
Description and Uses
Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.Mildronate (40 μM) inhibits the reaction of γ-butyrobetaine hydroxylase with γ-butyrobetaine with Km and Vmax of 36.8 μM and 0.08 nmol/min/mg protein, respectively.
Meldonium dihydrate has been used as an anti-ischemic agent to evaluate its protective effects on Ischemia-reperfusion (I/R) in chick embryos.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
