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A7290812

Sesamin , Analysis standard , 607-80-7

Synonym(s):
Fagarol

CAS NO.:607-80-7

Empirical Formula: C20H18O6

Molecular Weight: 354.35

MDL number: MFCD00216134

Pack Size Price Stock Quantity
20MG RMB79.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 121.0 to 125.0 °C
Boiling point: 504.4±50.0 °C(Predicted)
Density  1.385±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  Soluble in DMSO (>25 mg/ml)
form  crystalline
color  White
Merck  14,8470
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey PEYUIKBAABKQKQ-AFHBHXEDSA-N
LogP 4.064 (est)

Description and Uses

Sesamin (607-80-7) is a natural product derived from sesame seeds with anticancer1, antioxidant2, anti-inflammatory/immunomodulatory3, and antidiabetic4,5 effects. It also displayed effects on cholesterol and fatty acid metabolism.6? Sesamin was recently found to inhibit bacterial L-tryptophan indole lyase (Ki = 7 μM).7 This enzyme reacts with dietary tryptophan to produce the uremic toxin indoxyl sulfate which exacerbates chronic kidney disease.

Sesamin has been used:

  • as a lignan to study its effects on the osteoblastic differentiation of rat bone marrow stromal cells (BMSCs)
  • as a standard for the isolation of sesamin from sesame oil
  • as an enterolignan to study its effects on the proliferation of estrogen-receptor (ER)-positive human breast cancer MCF-7 cells

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P362+P364
Safety Statements  22-24/25
WGK Germany  3
HS Code  29329990

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