A7666712
Trimethyl borate , 98% , 121-43-7
Synonym(s):
Boric acid trimethyl ester;Methyl borate;Trimethyl borate
CAS NO.：121-43-7
Empirical Formula: C3H9BO3
Molecular Weight: 103.91
MDL number: MFCD00008346
EINECS: 204-468-9
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | -34 °C (lit.) |
| Boiling point: | 68-69 °C (lit.) |
| Density | 0.932 g/mL at 20 °C (lit.) |
| vapor density | 3.59 (vs air) |
| vapor pressure | 147.9-148 hPa ( 20 °C) |
| refractive index | n |
| Flash point: | 8 °F |
| storage temp. | Store at <= 20°C. |
| solubility | Miscible with tetrahydrofuran, ether, isoporpylamine, hexane and methanol. |
| form | Liquid |
| color | Colorless |
| Specific Gravity | 0.915 |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| Merck | 14,9712 |
| BRN | 1697939 |
| Dielectric constant | 8.2（20℃） |
| Exposure limits | ACGIH: TWA 200 ppm; STEL 250 ppm (Skin) OSHA: TWA 200 ppm(260 mg/m3) NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3) |
| Stability: | Stable. Incompatible with oxidizing agents. Decomposes slowly in the presence of moisture, rapidly in water. Flammable. |
| InChIKey | WRECIMRULFAWHA-UHFFFAOYSA-N |
| CAS DataBase Reference | 121-43-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Boric acid, trimethyl ester(121-43-7) |
| EPA Substance Registry System | Boric acid (H3BO3), trimethyl ester (121-43-7) |
Description and Uses
Trimethyl borate is a useful reagent in organic synthesis. It is involved in the production of resins, waxes and paints and acts as a methylation agent. As a boron source, Trimethyl borate is used to prepare flame retardants, anti-oxidants and corrosion inhibitors. It reacts with Grignard reagents followed by hydrolysis to prepare boronic acid. It is also used as a precursor of borate esters, which finds application in the Suzuki coupling reaction. It is used as neutron detector gas in the presence of a scintillation counter; as a promoter of diborane reactions.
Safety
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H225-H301+H311+H331-H319-H360FD-H370 |
| Precautionary statements | P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | Xn,F,T |
| Risk Statements | 11-21-23/25-36/37/38-10-36-61-60 |
| Safety Statements | 16-27-36/37/39-45-25-23-2-26-53 |
| RIDADR | UN 2416 3/PG 2 |
| WGK Germany | 3 |
| RTECS | ED5600000 |
| F | 21 |
| Autoignition Temperature | 305°C |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29209085 |
| Hazardous Substances Data | 121-43-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 6.14 ml/kg (Smyth) |
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
