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A7712358

Icaritin , 10mMinDMSO , 118525-40-9

Synonym(s):
3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

CAS NO.:118525-40-9

Empirical Formula: C21H20O6

Molecular Weight: 368.38

MDL number: MFCD22422519

Pack Size Price Stock Quantity
1ml RMB399.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 239℃
Boiling point: 582.0±50.0 °C(Predicted)
Density  1.359
Flash point: 206.7℃
storage temp.  2-8°C
solubility  DMSO: soluble5mg/mL, clear (warmed)
form  powder
pka 6.44±0.40(Predicted)
color  light yellow to dark yellow
λmax 368nm(MeOH)(lit.)
InChI InChI=1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
InChIKey TUUXBSASAQJECY-UHFFFAOYSA-N
SMILES C1(C2=CC=C(OC)C=C2)OC2=C(C/C=C(/C)\C)C(O)=CC(O)=C2C(=O)C=1O

Description and Uses

Icaritin is a hydrolytic product of Icariin, a traditional Chinese herbal medicine extracted from the Epimedium genus. Icaritin and Desmethylicaritin, is two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells. Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).

Safety

WGK Germany  3
RTECS  DJ3100870
HS Code  29329990

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