N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3- benzotriazin-3-yl)uronium tetrafluoroborate , 98% , 125700-69-8

CAS NO.：125700-69-8

Empirical Formula: C12H16BF4N5O2

Molecular Weight: 349.09

MDL number: MFCD00077730

PRODUCT Properties

• Melting point: 147 °C (dec.)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: acetonitrile: 0.1 g/mL, clear
• form: Powder or Solid
• color: White to yellow
• Sensitive: Moisture & Light Sensitive
• CAS DataBase Reference: 125700-69-8(CAS DataBase Reference)

Description and Uses

O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate (2-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate, TBTU) may be used as coupling reagent in the synthesis of macrocyclic polyamine derivatives with various length of linkers, condensation reagent in the large-scale preparation of the hematoregulatory nonapeptide (Glp-Glu-Asp)2-DAS-(Lys)2 (2,SK&F 107647), coupling reagent for peptide synthesis which best suppresses racemization during fragment condensation.

Safety

• Symbol(GHS): GHS07
• Signal word: Danger
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi
• Risk Statements: 37-36/37/38
• Safety Statements: 22-24/25-36-26
• RIDADR: UN 1759 8/PG III
• WGK Germany: 3
• F: 8-10-21
• HazardClass: 8
• PackingGroup: III
• HS Code: 29339900