Madecassicacid , 10mMinDMSO , 18449-41-7
Synonym(s):
6β-Hydroxyasiatic acid;Brahmic acid
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB399.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 270°C (dec.) |
| Boiling point: | 641.7±55.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
| pka | 4.63±0.70(Predicted) |
| form | Solid |
| color | White to Pale Red |
| InChIKey | PRAUVHZJPXOEIF-MRQYELSVNA-N |
| LogP | 4.321 (est) |
Description and Uses
Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; ). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.
wound healing
Safety
| Symbol(GHS) |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301-H410 |
| Precautionary statements | P501-P273-P270-P264-P391-P301+P310+P330-P405 |
| Hazard Codes | Xi |
| Safety Statements | 24/25 |
| HS Code | 29389090 |
