2,2,6,6-Tetramethylpiperidine , ≥98.0%(GC) , 768-66-1

Synonym(s):
2,2,6,6-Tetramethylpiperidine

CAS NO.：768-66-1

Empirical Formula: C9H19N

Molecular Weight: 141.25

MDL number: MFCD00005985

EINECS: 212-199-3

PRODUCT Properties

• Melting point: -59°C
• Boiling point: 152 °C (lit.)
• Density: 0.837 g/mL at 25 °C (lit.)
• vapor pressure: 14 hPa (39 °C)
• refractive index: n20/D 1.445(lit.)
• Flash point: 76 °F
• storage temp.: Store below +30°C.
• solubility: MISCIBLE
• pka: 11.07(at 25℃)
• form: Liquid
• color: Clear colorless to yellow
• Specific Gravity: 0.837
• Water Solubility: MISCIBLE
• Sensitive: Air Sensitive
• BRN: 103296
• InChIKey: RKMGAJGJIURJSJ-UHFFFAOYSA-N
• CAS DataBase Reference: 768-66-1(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 2,2,6,6-tetramethyl-(768-66-1)
• EPA Substance Registry System: Piperidine, 2,2,6,6-tetramethyl- (768-66-1)

Description and Uses

2,2,6,6-Tetramethylpiperidine is a hindered base used to prepare metallo-amide bases and selective generation of silylketene acetals. It is used in the preparation of hibarimicinone, (Z)-silylketene acetal and 4-substituted quinazoline. It acts as a precursor to Lithium tetramethylpiperidide and (2,2,6,6-Tetramethylpiperidin-1-yl)oxyl radical.

Safety

• Symbol(GHS): GHS02,GHS05,GHS07
• Signal word: Danger
• Hazard statements: H226-H290-H302-H314
• Precautionary statements: P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
• Hazard Codes: Xn,F,C
• Risk Statements: 10-22-36/37/38
• Safety Statements: 26-37/39-16
• RIDADR: UN 1992 3/PG 3
• WGK Germany: 2
• RTECS: TN4220000
• Autoignition Temperature: 290 °C
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• HS Code: 29333999
• Toxicity: LD50 orally in Rabbit: 500 mg/kg
• Limited Quantities: 5.0 L (1.3 gallons) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)