1,2,4-Triazolo[4,3-<i>a</i>]pyridin-3(2<i>H</i>)-one , >98.0%(HPLC) , 6969-71-7

Synonym(s):
3-Hydroxytriazolo[4,3-a]pyridine;s-Triazolo[4,3-a]pyridin-3-ol

CAS NO.：6969-71-7

Empirical Formula: C6H5N3O

Molecular Weight: 135.12

MDL number: MFCD00022632

EINECS: 230-191-8

PRODUCT Properties

• Melting point: 231°C
• Density: 1.51±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• pka: 7.86±0.20(Predicted)
• form: Solid
• color: Light Brown to Brown
• BRN: 607433
• Stability: Light Sensitive
• InChI: InChI=1S/C6H5N3O/c10-6-8-7-5-3-1-2-4-9(5)6/h1-4H,(H,8,10)
• InChIKey: LJRXNXBFJXXRNQ-UHFFFAOYSA-N
• SMILES: C12=NNC(=O)N1C=CC=C2
• LogP: 0.113
• CAS DataBase Reference: 6969-71-7(CAS DataBase Reference)

Description and Uses

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one was used to prepare a congener of Trazodone (T718500) which was found to be a potent and selective inhibitor of synaptosomal uptake of 5-hydroxytryptamine.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 29339900