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A8337232

Aldosterone standard , 100μg/mLinacetonitrile , 52-39-1

Synonym(s):
11β,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al;11β,21-Dihydroxypregn-4-ene-3,18,20-trione;18-Aldocorticosterone;Aldosterone;Reichstein X

CAS NO.:52-39-1

Empirical Formula: C21H28O5

Molecular Weight: 360.45

MDL number: MFCD00051136

EINECS: 200-139-9

Pack Size Price Stock Quantity
1ML RMB1599.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 170-172°C
alpha  D23 +152.2° (anhydr; c = 2 in acetone); D25 +161° (c = 0.1 in chloroform)
Boiling point: 412.46°C (rough estimate)
Density  1.28
refractive index  1.6120 (estimate)
Flash point: 2℃
storage temp.  Sealed in dry,Room Temperature
solubility  Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 12.98±0.10(Predicted)
form  Crystalline Powder
color  White
optical activity +14523 (c 0.99, acetone)
Water Solubility  51.18mg/L(37 ºC)
Merck  13,224
BRN  3224996
CAS DataBase Reference 52-39-1(CAS DataBase Reference)
EPA Substance Registry System Aldosterone (52-39-1)

Description and Uses

Aldosterone is a mineralocorticosteroid that takes part in the regulation of electrolytic balance in the organism. Aldosterone lowers excretion of sodium ions from the body, thus increasing their reabsorption and increasing secretion of potassium ions in renal tubules. Being a competitive antagonist of aldosterone, spironlactone blocks aldosterone receptors, thus increasing excretion of sodium, chloride, and corresponding equivalents of water with urine, thus retaining the amount of potassium ions in the organism. Spironolactone is used both individually as well as in combination with thiazides, since it lowers kaliuresis caused by thiazide diuretics.

Imatinib intermediate

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P280-P305+P351+P338
Hazard Codes  Xi,Xn,F
Risk Statements  36/37/38-36-20/21/22-11
Safety Statements  22-24/25-36-26-36/37-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS  TU4523000
22-24-25
HS Code  29372900