(S)-(2-Chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone , 97% , 915095-87-3

CAS NO.：915095-87-3

Empirical Formula: C17H14ClIO3

Molecular Weight: 428.65

MDL number: MFCD22665921

PRODUCT Properties

• Melting point: 109-113oC
• Boiling point: 526℃
• Density: 1.639
• Flash point: 272℃
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
• form: Solid
• color: Off-White to Pale Beige
• optical activity: Consistent with structure
• InChI: InChI=1S/C17H14ClIO3/c18-16-6-3-12(19)9-15(16)17(20)11-1-4-13(5-2-11)22-14-7-8-21-10-14/h1-6,9,14H,7-8,10H2/t14-/m0/s1
• InChIKey: WBBJCIOCSVFCNI-AWEZNQCLSA-N
• SMILES: C(C1=CC(I)=CC=C1Cl)(C1=CC=C(O[C@H]2CCOC2)C=C1)=O

Description and Uses

(2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone is an intermediate of Empagliflozin (E521510) which is a potent and selective SGLT-2 inhibitor that improves glycaemic control syndrome in diabetic rats.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319
• Precautionary statements: P261-P305+P351+P338