(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoicacid , 95% , 851307-12-5

CAS NO.：851307-12-5

Empirical Formula: C15H19F2NO4

Molecular Weight: 315.31

MDL number:

PRODUCT Properties

• Boiling point: 444.3±45.0 °C(Predicted)
• Density: 1.243±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• pka: 4.37±0.10(Predicted)
• Appearance: white solid
• InChI: InChI=1/C15H19F2NO4/c1-15(2,3)22-14(21)18-11(8-13(19)20)6-9-4-5-10(16)7-12(9)17/h4-5,7,11H,6,8H2,1-3H3,(H,18,21)(H,19,20)/t11-/s3
• InChIKey: LUYHWLQWAVCDNA-LBPXTSNRNA-N
• SMILES: C(O)(=O)C[C@H](NC(OC(C)(C)C)=O)CC1=CC=C(F)C=C1F |&1:4,r|

Description and Uses

(3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4-difluorophenyl)butanoic Acid is a derivative of Sitagliptin (S491000), a dipeptidyl peptidase-4 inhibitor used to treat patients with type-2 diabetes by means of glycemic control.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H320-H335
• Precautionary statements: P264-P270-P301+P312-P330