Home Categories 7-Fluoro-4-hydroxy-2H-chromen-2-one
BD9527355

7-Fluoro-4-hydroxy-2H-chromen-2-one , 98% , 2145-27-9

Synonym(s):
7-Fluoro-4-hydroxy-1(2H)-benzopyran-2-one;7-Fluoro-4-hydroxy-2H-chromen-2-one

CAS NO.:2145-27-9

Empirical Formula: C9H5FO3

Molecular Weight: 180.13

MDL number: MFCD11845381

Pack Size Price Stock Quantity
100mg RMB276.00 In Stock
250mg RMB463.20 In Stock
1g RMB976.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 220-225°C
Boiling point: 339.4±42.0 °C(Predicted)
Density  1.549±0.06 g/cm3(Predicted)
pka 4.50±1.00(Predicted)
form  solid

Description and Uses

Reactant for:

  • Enantioselective synthesis of polycyclic coumarins via in situ formed primary amine-imine-catalyzed asymmetric Michael addition to cyclic enones
  • Preparation of dicoumarol analogs as inhibitors of human NAD(P)H quinone oxidoreductase-1 (NQO1) as agents active against human pancreatic and colon cancer cells
  • Imidazolidinecarboxylic acid-catalyzed asymmetric Michael reaction with unsaturated ketones in a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant
  • Asymmetric synthesis of functionalized α-keto esters and their hemiketal and hemiaminal derivatives via direct Michael addition with unsaturated α-keto esters catalyzed by bisoxazoline-copper(II) complexes

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3