![[3-(hydroxymethyl)-2-nitrophenyl]methanol](https://img.chemicalbook.com/CAS/GIF/16578-60-2.gif)
LN-398932
[3-(hydroxymethyl)-2-nitrophenyl]methanol , 16578-60-2
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 100-101 °C |
| Boiling point: | 366.9±32.0 °C(Predicted) |
| Density | 1.420±0.06 g/cm3(Predicted) |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.68±0.10(Predicted) |
| color | Off White to Pale Yellow |
Description and Uses
2-Nitro-1,3-benzenedimethanol is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.