LN-565427
(2-(4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenylamino)quinazolin-6-ylamino)-4-methyl-4,5-dihydrooxazol-4-yl)methanol , 98% HPLC , 937263-81-5
Update time: 2023-04-23
PRODUCT Properties
Density | 1.47±0.1 g/cm3(Predicted) |
pka | 14.22±0.10(Predicted) |
form | Solid |
color | White to off-white |
Description and Uses
ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 (IC50=7.9 μM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 μM)[1].
Safety
Symbol(GHS) | ![]() GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |