LN-909032
Venadaparib , 98% , 1681017-83-3
CAS NO.：1681017-83-3
Empirical Formula: C23H23FN4O2
Molecular Weight: 406.45
MDL number: MFCD34470861
Update time: 2023-04-23
PRODUCT Properties
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 100 mg/mL (246.03 mM; Need ultrasonic) |
| form | Solid |
| pka | 12.06±0.40(Predicted) |
| color | White to yellow |
Description and Uses
Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research[1][2].