LN3966049
SLM6031434(hydrochloride) , ≥98% , 1897379-34-8
CAS NO.：1897379-34-8
Empirical Formula: C22H31ClF3N5O2
Molecular Weight: 489.962
MDL number: MFCD31689247
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1296.00 | In Stock |
|
| 10mg | RMB2212.00 | In Stock |
|
| 25mg | RMB5248.00 | In Stock |
|
| 50mg | RMB9316.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Store at -20°C |
| solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 5 mg/ml |
| form | A crystalline solid |
| color | white to beige |
| Water Solubility | water: ≥2mg/mL |
Description and Uses
SLM 6031434 Hydrochloride is a Sphk2 inhibitor (Ki = 0.4 μM for mouse Sphk2). Exhibts some selectivity for Sphk2 over Sphk1 (Ki > 20 μM). Decreases levels of sphingosine-1-phosphate (S1P) in U937 cells in vitro and increases blood levels of S1P in wild-type mice.