PRODUCT Properties
| Melting point: | 212-213 °C |
| Density | 1.0476 (rough estimate) |
| refractive index | 1.5650 (estimate) |
| storage temp. | -20°C |
| form | powder |
| pka | 1.42±0.50(Predicted) |
| color | Colorless to light yellow |
Description and Uses
Taurolithocholic acid is a bile acid that has the activity of increasing cell viability, inducing the S phase of the cell cycle, and promoting DNA synthesis in a concentration-dependent manner in the intrahepatic cholangiocarcinoma cell line RMCCA-1. It can also increase the phosphorylation of EGFR and ERK 1/2 and the expression of cyclin D1 in RMCCA-1 cells, and its induced RMCCA-1 cell growth can be inhibited by specific antagonists and inhibitors.
Safety
| Symbol(GHS) |   GHS02,GHS08 |
| Signal word | Danger |
