98% , 120511-88-8

CAS NO.：120511-88-8

Empirical Formula: C15H18N2O

Molecular Weight: 242.32

MDL number:

PRODUCT Properties

• Melting point: 150-160℃
• Boiling point: 382.3±37.0 °C(Predicted)
• Density: 1.084
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: 14.34±0.10(Predicted)
• color: White to Off-White
• InChI: InChI=1S/C15H18N2O/c1-14(2,9-16)12-5-11(8-18)6-13(7-12)15(3,4)10-17/h5-7,18H,8H2,1-4H3
• InChIKey: PLEAQICJSGOGID-UHFFFAOYSA-N
• SMILES: C1(C(C)(C)C#N)=CC(CO)=CC(C(C)(C)C#N)=C1

Description and Uses

2-[3-(Cyanodimethylmethyl)-5-hydroxymethylphenyl]-2-methylpropionitrile (Anastrozole EP Impurity E ) is an impurity of Anastrozole (A637425), an aromatase inhibitor which functions as an antineoplastic (1,2). Anastrozole is used in post-menopausal women with advanced breast cancer.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H317
• Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P321-P363-P501