Propargyl-PEG8-bromide , 97% , 2055046-25-6

CAS NO.：2055046-25-6

Empirical Formula: C19H35BrO8

Molecular Weight: 471.38

MDL number: MFCD29042377

PRODUCT Properties

• Boiling point: 491.5±40.0 °C(Predicted)
• Density: 1.208±0.06 g/cm3(Predicted)

Description and Uses

Propargyl-PEG8-bromide is a PEG reagent containing an alkyne group and a bromide group. The alkyne group canreacts with azide-bearing compounds or biomolecules in Click Chemistry reactions under the catalyzation of copper. The PEG spacer increases water-solubility of the molecule in aqueous media.

Propargyl-PEG8-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.