M3755857
PR-39 , ≥95% , 139637-11-9
CAS NO.:139637-11-9
Empirical Formula: C229H345N69O41
Molecular Weight: 4720.63
MDL number: MFCD03458161
Pack Size | Price | Stock | Quantity |
5mg | RMB5760.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
storage temp. | Desiccate at -20°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | Powder |
Description and Uses
PR-39, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 reversibly binds to the α7 subunit of the proteasome and blocks degradation of NF-κB inhibitor IκBα by the ubiquitin-proteasome pathway. PR-39 stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice[1][2].