Propargyl-PEG9-bromide , 98% , 2055042-83-4

CAS NO.：2055042-83-4

Empirical Formula: C21H39BrO9

Molecular Weight: 515.43

MDL number: MFCD29079385

PRODUCT Properties

• Boiling point: 525.6±45.0 °C(Predicted)
• Density: 1.200±0.06 g/cm3(Predicted)

Description and Uses

Propargyl-PEG9-bromide consists of a propargyl group and a bromide group. The propargyl group reacts with azide compounds in copper catalyzed Click Chemistry reactions. The bromide (Br)can be used as a leaving group for nucleophilic substitution reactions. The 9-unit PEG spacer improves the hydrophilicity of the molecule.

Propargyl-PEG9-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG9-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.