M3820857
SJFα , ≥98% , 2254609-27-1
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB3609.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 1230.3±65.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 13.14±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
Description and Uses
SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC50 of 7.16??nM, but is far less effective at degrading p38δ (DC50=299?nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5?μM[1].