PRODUCT Properties
Melting point: | <25℃ |
Boiling point: | 474.94°C (rough estimate) |
Density | 0.9882 (rough estimate) |
refractive index | 1.4480 (estimate) |
Flash point: | -23 °C |
storage temp. | 2-8°C |
solubility | Chloroform (Sparingly), Ethanol (Slightly), Ethyl Acetate (Slightly), Methanol ( |
pka | 11.05±0.40(Predicted) |
form | Oil |
color | Colourless to Yellow |
InChIKey | WGVKWNUPNGFDFJ-UHFFFAOYSA-N |
LogP | 10.724 (est) |
Description and Uses
(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an EC50 value of 68.2 μM. (±)-β-Tocopherol (100 μM) inhibits LPS-induced COX-2 gene expression in mouse RAW 264.7 macrophage cells. Unlike (±)-α-tocopherol , (±)-β-tocopherol does not inhibit smooth muscle cell proliferation, decrease PKC activity, increase phosphoprotein phosphatase 2A (PP2A) activity, or modify expression of the α-tropomyosin gene. [Matreya, LLC. Catalog No. 1071]
One of the naturally occurring forms of Vitamin E. Is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.
Safety
Symbol(GHS) | GHS02,GHS07,GHS08,GHS09 |
Signal word | Danger |
Hazard statements | H225-H304-H315-H336-H361f-H373-H411 |
Precautionary statements | P210-P260-P280-P301+P310-P370+P378-P403+P235 |
Hazard Codes | F,Xn,N |
Risk Statements | 11-38-48/20-51/53-62-67-65 |
Safety Statements | 36/37-61-62-16 |
RIDADR | UN1208 3/PG 2 |
WGK Germany | 3 |