tert-Butyl3-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)propanoate , 97% , 1374658-84-0

CAS NO.：1374658-84-0

Empirical Formula: C14H24O5

Molecular Weight: 272.34

MDL number: MFCD22201522

PRODUCT Properties

• Boiling point: 337.2±27.0 °C(Predicted)
• Density: 1.023±0.06 g/cm3(Predicted)
• form: Liquid
• color: Colorless to light yellow

Description and Uses

Propargyl-PEG3-t-butyl ester consists of an alkyne group and a t-butyl ester group. The alkyne groupreacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The protected carboxyl group can be deprotected under acidic conditions.

Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.