1-PalmitoylLysophosphatidicAcid(1-PalmitoylLPAfreeacid) , 98% , 22002-85-3

CAS NO.：22002-85-3

Empirical Formula: C19H39O7P

Molecular Weight: 410.48

MDL number:

EINECS: 2447074

PRODUCT Properties

• Boiling point: 560.6±60.0 °C(Predicted)
• Density: 1.112±0.06 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMF: 2 mg/ml; DMSO: 2.5 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 3 mg/ml
• form: A crystalline solid
• pka: 1.82±0.10(Predicted)
• color: White to off-white

Description and Uses

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.^1,2 Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca²⁺ and Mg²⁺.³