Home Categories Chemical Reagents (2-Hydroxypropyl)-α-cyclodextrin
S678478

(2-Hydroxypropyl)-α-cyclodextrin , averageMw~1,180 , 128446-33-3

Synonym(s):
α‐HPCD;2‐hydroxypropyl‐α‐CD;2OHpαCD;HPαCD;HP-α-CD

CAS NO.:128446-33-3

Empirical Formula:

Molecular Weight:

MDL number: MFCD00197866

Pack Size Price Stock Quantity
5g RMB423.01 In Stock
25g RMB1366.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 245 °C (dec.)(lit.)
Density  1.39 at 24.6℃
solubility  Soluble in water, methanol, DMF. Insoluble in acetone, chloroform.
form  Solid powder
color  White to off white
optical activity [α]20/D +125°, c = 1 in H2O
LogP -10.6--9.89
Surface tension 66.1mN/m at 1g/L and 20℃
EPA Substance Registry System .alpha.-Cyclodextrin, 2-hydroxypropyl ethers (128446-33-3)

Description and Uses

  • (2-Hydroxypropyl)-α-cyclodextrin can be used as a chiral selector to resolve tryptophan racemate by capillary electrophoresis.
  • It can be used to synthesize biodegradable polyrotaxanes for fabricating blood-contacting devices.
  • Co-polymer based on (2-hydroxypropyl)-α-cyclodextrin cross-linked with polyethylenimine can be used as a gene delivery vector.
  • It can also be used as stabilizer for antibacterial iodine formulations, as it forms a stable inclusion complex with iodine and improves aqueous solubility.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
WGK Germany  3

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