A0534550
NPPB , ≥97％ , 107254-86-4
Synonym(s):
5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem;NPPB;NPPB, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II, ANO Blocker II, Anoctamin Blocker II
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB119.20 | In Stock |
|
| 50mg | RMB476.80 | In Stock |
|
| 250mg | RMB1908.80 | In Stock |
|
| 1g | RMB5343.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 178-180℃ |
| Boiling point: | 523.5±50.0 °C(Predicted) |
| Density | 1.323±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | ethanol: 3 mg/mL |
| pka | 2.27±0.22(Predicted) |
| form | Yellow solid |
| color | Light yellow to yellow |
| InChI | 1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20) |
| InChIKey | WBSMIPAMAXNXFS-UHFFFAOYSA-N |
| SMILES | OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O |
Description and Uses
NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
