A0645612
2-Amino-4-chlorophenol , 97% , 95-85-2
Synonym(s):
2-Amino-4-chlorophenol;5-Chloro-2-hydroxyaniline
CAS NO.：95-85-2
Empirical Formula: C6H6ClNO
Molecular Weight: 143.57
MDL number: MFCD00007694
EINECS: 202-458-9
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 136-141 °C(lit.) |
| Boiling point: | 185.5°C (rough estimate) |
| Density | 1.2028 (rough estimate) |
| refractive index | 1.5618 (estimate) |
| storage temp. | 2-8°C |
| solubility | 2.3g/l |
| form | Solid |
| pka | 9.31±0.18(Predicted) |
| Colour Index | 76525 |
| color | Pale Orange to Light Brown |
| Water Solubility | Insoluble. <0.1 g/100 mL at 20 ºC |
| BRN | 774859 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | SWFNPENEBHAHEB-UHFFFAOYSA-N |
| CAS DataBase Reference | 95-85-2(CAS DataBase Reference) |
| IARC | 2B (Vol. 123) 2020 |
| NIST Chemistry Reference | 5-Chloro-2-hydroxyaniline(95-85-2) |
| EPA Substance Registry System | 2-Amino-4-chlorophenol (95-85-2) |
Description and Uses
2-Amino-4-chlorophenol is a widely used reagent in the synthesis of various drugs, dyes and pesticides. A reagent in the synthesis of aggrecanase-2 inhibitors based on acylthiosemicarbazide zinc-binding, used in the treatment of osteoarthritis.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302-H351 |
| Precautionary statements | P202-P264-P270-P280-P301+P312-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38-20/21/22 |
| Safety Statements | 26-36-36/37/39 |
| RIDADR | UN 2673 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | SJ5700000 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29222900 |
