Ammothamnine , Analysis standard , 16837-52-8

CAS NO.：16837-52-8

Empirical Formula: C15H24N2O2

Molecular Weight: 264.36

MDL number: MFCD00210339

EINECS: 605-514-4

PRODUCT Properties

• Melting point: 208℃
• storage temp.: Inert atmosphere,2-8°C
• solubility: methanol: soluble10mg/mL, clear, colorless
• pka: 4.87±0.20(Predicted)
• form: powder
• color: white to off-white
• Stability: Hygroscopic
• InChI: InChI=1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15?,17+/m0/s1
• InChIKey: XVPBINOPNYFXID-LHDUFFHYSA-N
• SMILES: [N@@+]12([O-])CCC[C@]3([H])C1[C@@]([H])([C@@]1([H])CCCC(=O)N1C3)CCC2

Description and Uses

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine. It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine. Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling. This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.

antifungal, hepatoprotectant

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264b-P270-P301+P312-P330-P403-P501c
• Hazard Codes: Xn
• Risk Statements: 22-20/22
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: OQ1770000
• HS Code: 29399990
• Hazardous Substances Data: 16837-52-8(Hazardous Substances Data)