Azimsulfuron , Analysis standard , 120162-55-2

Synonym(s):
N-{[(4,6-Dimethoxy-2-pyrimidinyl)amino]carbonyl}-1-methyl-4-(2-methyl-H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide

CAS NO.：120162-55-2

Empirical Formula: C13H16N10O5S

Molecular Weight: 424.4

MDL number: MFCD02102190

PRODUCT Properties

• Melting point: 170°
• Density: 1.74±0.1 g/cm3(Predicted)
• storage temp.: Sealed in dry,2-8°C
• solubility: Solubility in organic solvents (g/l at 25 °C); Acetone 26.4; Acetonitrile 13.9; Ethyl acetate 13.0; Dichloromethane 65.9; n‐Hexane <0.2; Methanol 2.1; Toluene 1.8
• pka: 3.6(at 25℃)
• form: Solid
• color: White to Off-White
• Water Solubility: Solubility in water (g/l at 20 °C): 0.072 (pH 5) 1.050 (pH 7) 6.536 (pH 9).
• BRN: 8284859
• Henry's Law Constant: 2.0×10⁹ mol/(m³Pa) at 25℃, Maniere et al. (2011)
• Major Application: agriculture; environmental
• InChI: 1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)
• InChIKey: MAHPNPYYQAIOJN-UHFFFAOYSA-N
• SMILES: COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2c(cnn2C)-c3nnn(C)n3)n1
• LogP: 0.650
• CAS DataBase Reference: 120162-55-2(CAS DataBase Reference)
• EPA Substance Registry System: Azimsulfuron (120162-55-2)

Description and Uses

A sulfonylurea herbicide for the control of a range of broadleaved and sedge weeds in paddy fields and other crops. It is highly soluble in water, semi-volatile and, based on its physico-chemical properties, appears to have potential for leaching to groundwater. It is not expected to be persistent in the field but can be persistent in water systems. It has a low mammalian toxicity but has high potential for bioaccumulation. No adverse health effects have been identified. Azimsulfuron is moderately toxic to algae, honeybees and earthworms but less so to birds and fish.

Azimsulfuron may be used as an analytical reference standard for the determination of the pesticide in:

• Paddy field water by direct injection using liquid chromatography-hybrid triple quadrupole-linear ion trap-mass spectrometry (LC-QqLIT-MS).
• Tap and leaching water samples by solid-phase extraction (SPE), followed by LC coupled to tandem mass spectrometry (LC-MS/MS).

Safety

• Symbol(GHS): GHS09
• Signal word: Warning
• Hazard statements: H410
• Precautionary statements: P273
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: N
• Risk Statements: 50/53
• Safety Statements: 60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: WGK 2
• HS Code: 29350090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Aquatic Acute 1; Aquatic Chronic 1
• Toxicity: LD50 in rats, bobwhite quail, mallard duck (mg/kg): >5000, >2250, >2250 orally; in rats (mg/kg): >2000 dermally (Marquez); LC50 (96 hr) in carp, bluegill sunfish, rainbow trout (ppm): >300, >1000, 154 (Marquez)