4-Amino-2-chloro-6,7-dimethoxyquinazoline , >98.0%(HPLC) , 23680-84-4

Synonym(s):
2-Chloro-6,7-dimethoxy-4-quinazolinamine;4-Amino-2-chloro-6,7-dimethoxyquinazoline

CAS NO.：23680-84-4

Empirical Formula: C10H10ClN3O2

Molecular Weight: 239.66

MDL number: MFCD00051734

EINECS: 245-821-7

PRODUCT Properties

• Melting point: 262-268 °C (dec.)(lit.)
• Boiling point: 374.0±42.0 °C(Predicted)
• Density: 1.5062 (rough estimate)
• vapor pressure: 0Pa at 25℃
• refractive index: 1.5500 (estimate)
• storage temp.: 2-8°C
• solubility: DMSO (Sparingly, Heated), Methanol (Slightly, Heated)
• form: Solid
• pka: 4.35±0.30(Predicted)
• color: White to Off-White
• Water Solubility: 1.418g/L at 25℃
• BRN: 747463
• Major Application: pharmaceutical (small molecule)
• InChI: 1S/C10H10ClN3O2/c1-15-7-3-5-6(4-8(7)16-2)13-10(11)14-9(5)12/h3-4H,1-2H3,(H2,12,13,14)
• InChIKey: HWIIAAVGRHKSOJ-UHFFFAOYSA-N
• SMILES: COc1cc2nc(Cl)nc(N)c2cc1OC
• LogP: 1.5 at 25℃
• CAS DataBase Reference: 23680-84-4(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-2-chloro-6,7-dimethoxyquinazoline(23680-84-4)

Description and Uses

Intermediate in the production on Terazosin.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• target organs: Respiratory system
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 10
• HazardClass: IRRITANT
• HS Code: 29339900
• Storage Class: 13 - Non Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3