1-Aminocyclopentanecarboxylic Acid , >98.0% , 52-52-8

Synonym(s):
1-Aminocyclopentanecarboxylic acid

CAS NO.：52-52-8

Empirical Formula: C6H11NO2

Molecular Weight: 129.16

MDL number: MFCD00001381

EINECS: 200-144-6

PRODUCT Properties

• Melting point: 320 °C (dec.) (lit.)
• Boiling point: 239.22°C (rough estimate)
• Density: 1.1426 (rough estimate)
• refractive index: 1.4827 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: DMSO: < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
• form: Crystalline Flakes or Powder
• pka: 2.38±0.20(Predicted)
• color: White to beige
• Water Solubility: 5 g/100 mL
• Merck: 14,2734
• BRN: 636626
• CAS DataBase Reference: 52-52-8(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 1-amino-(52-52-8)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 1-amino- (52-52-8)

Description and Uses

Cycloleucine can be used as a building block to synthesize:

• Phosphonylmethylaminocyclopentane-1-carboxylic acid by reacting with paraformaldehyde and diethylphosphite via Kabachnik-Field′s reaction.
• Benzo[b]thiophene-2-carboxylic acid {1-[1-(R)-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethylcarbamoyl]cyclopentyl}-amide, (MEN14268) as potential tachykinin NK2 receptor antagonist.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P301+P310+P330
• Hazard Codes: Xn,Xi
• Risk Statements: 22
• Safety Statements: 22-24/25
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: GY2625000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29224999
• Hazardous Substances Data: 52-52-8(Hazardous Substances Data)
• Toxicity: LD50 oral in rat: 290mg/kg
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)