1-Adamantanamine Sulfate , ≥98.0% , 31377-23-8

Synonym(s):
1-Aminoadamantane sulfate, Adamantylamine sulfate;Amantadine sulfate

CAS NO.：31377-23-8

Empirical Formula: C20H36N2O4S

Molecular Weight: 400.58

MDL number: MFCD00077251

EINECS: 250-604-5

PRODUCT Properties

• Melting point: 300 °C
• storage temp.: Store below +30°C.
• solubility: Aqueous Acid (Slightly), Aqueous Base (Slightly)
• form: Fine Crystalline Powder
• color: White
• PH: 4.9 (100g/l, H2O, 20°C) (slurry)
• Stability: Hygroscopic
• InChI: InChI=1S/C10H17N.H2O4S/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;1-5(2,3)4/h7-9H,1-6,11H2;(H2,1,2,3,4)
• InChIKey: MYWTWSQFJLXGGQ-JUMAMQMDSA-N
• SMILES: NC12CC3CC(CC(C3)C1)C2.S(O)(O)(=O)=O
• CAS DataBase Reference: 31377-23-8(CAS DataBase Reference)

Description and Uses

Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research[1][2][3][4][5][6].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Safety Statements: 24/25
• WGK Germany: WGK 3 highly water endangering
• HS Code: 2921 30 99