2-<WBR>Amino-<WBR>5-<WBR>trifluoromethyl-<WBR>1,3,4-<WBR>thiadiazole , 97% , 10444-89-0

CAS NO.：10444-89-0

Empirical Formula: C3H2F3N3S

Molecular Weight: 169.13

MDL number: MFCD00003109

EINECS: 233-930-2

PRODUCT Properties

• Melting point: 220-225 °C
• Boiling point: 182.2±50.0 °C(Predicted)
• Density: 1.672±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C(protect from light)
• solubility: methanol: soluble0.25g/10 mL, clear, colorless
• pka: 0.30±0.10(Predicted)
• form: powder to crystal
• color: White to Almost white
• BRN: 513140
• InChI: InChI=1S/C3H2F3N3S/c4-3(5,6)1-8-9-2(7)10-1/h(H2,7,9)
• InChIKey: LTEUXHSAYOSFGQ-UHFFFAOYSA-N
• SMILES: S1C(C(F)(F)F)=NN=C1N
• CAS DataBase Reference: 10444-89-0(CAS DataBase Reference)
• EPA Substance Registry System: 1,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)- (10444-89-0)

Description and Uses

2-Amino-5-trifluoromethyl-1,3,4-thiadiazole was used in the synthesis of:

• series of 2-sulfonamido/trifluoromethyl-6-(4μ-substituted aryl/heteroaryl)imidazo[2,1-b]-1,3,4-thiadiazole derivatives
• 2-trifluoromethyl/sulfonamido-5,6-diarylsubstituted imidazo[2,1-b]-1,3,4-thiadiazole derivatives
• bicyclic bridgehead itrogen heterocycles

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 37/39-26
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• HS Code: 29349990