2-<WBR>Amino-<WBR>3-<WBR>bromopyridine , 97% , 13534-99-1

CAS NO.：13534-99-1

Empirical Formula: C5H5BrN2

Molecular Weight: 173.01

MDL number: MFCD03095187

EINECS: 629-620-5

PRODUCT Properties

• Melting point: 63-67 °C
• Boiling point: 232.0±20.0 °C(Predicted)
• Density: 1.6065 (rough estimate)
• vapor pressure: 0.83-1.8Pa at 20-25℃
• refractive index: 1.5182 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• pka: 4.14±0.36(Predicted)
• form: Powder
• color: Gray to brown
• BRN: 109867
• InChI: InChI=1S/C5H5BrN2/c6-4-2-1-3-8-5(4)7/h1-3H,(H2,7,8)
• InChIKey: RBCARPJOEUEZLS-UHFFFAOYSA-N
• SMILES: C1(N)=NC=CC=C1Br
• LogP: 1.5 at 20℃ and pH7
• CAS DataBase Reference: 13534-99-1(CAS DataBase Reference)

Description and Uses

2-Amino-3-bromopyridine may be used to synthesize:

• 2-acylamido-3-bromopyridines
• 2-anilino-3-bromopyridine
• 3-[(2-methoxyphenyl)ethynyl]pyridin-2-amine
• 3-[(4-methoxyphenyl)ethynyl]pyridin-2-amine
• N-(bromopyridyl)amidines
• carbolines via palladium catalyzed arylation followed by palladium catalyzed amination reaction
• 2-amino-3-cyanopyridine via palladium catalyzed cyanation reaction with potassium ferro-cyanide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene [DBU]
• nitro-substituted N,N′-dipyridinylamines via palladium catalyzed coupling reaction with 2-chloro-3-nitropyridine in the presence of Xantphos ligand
• 2-amino-3-iodopyridine via reaction with sodium iodide in the presence of copper(I)iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• PackingGroup: II
• HS Code: 29333990