A0969950
Thalidomide,propargyl , ≥95%(HPLC) , 2098487-39-7
CAS NO.：2098487-39-7
Empirical Formula: C16H12N2O5
Molecular Weight: 312.277
MDL number: MFCD32063450
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB575.20 | In Stock |
|
| 10mg | RMB975.20 | In Stock |
|
| 25mg | RMB1951.20 | In Stock |
|
| 50mg | RMB3512.00 | In Stock |
|
| 100mg | RMB6319.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 590.2±50.0 °C(Predicted) |
| Density | 1.469±0.06 g/cm3(Predicted) |
| form | Solid |
| pka | 10.68±0.40(Predicted) |
| color | White to off-white |
Description and Uses
Thalidomide-propargyl is an alkyne-functionalized Thalidomide.
Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs[1]. Thalidomide-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.