TenofovirAlafenamideHemifumarate , 95% , 1392275-56-7

CAS NO.：1392275-56-7

Empirical Formula: C25H33N6O9P

Molecular Weight: 592.55

MDL number: MFCD30534429

EINECS: 805-448-8

PRODUCT Properties

• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMSO:75.0(Max Conc. mg/mL);70.16(Max Conc. mM)
• form: Solid
• color: White to off-white
• InChIKey: MEJAFWXKUKMUIR-GQDWUREHNA-N
• SMILES: C(/C(=O)O)=C\C(=O)O.C(N1C=NC2=C(N=CN=C12)N)[C@@H](C)OCP(=O)(N[C@@H](C)C(=O)OC(C)C)OC1C=CC=CC=1 |&1:19,26,r|
• CAS DataBase Reference: 1392275-56-7

Description and Uses

Tenofovir alafenamide hemifumarate is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.

Tenofovir alafenamide hemifumarate is a newer, more effective prodrug used in combination with FTC that has recently been approved for the prevention of HIV transmission through the rectum. It is used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338