Boc-His-OH , 98% , 17791-52-5

Synonym(s):
N_α-(tert-Butoxycarbonyl)-L-histidine;N_α-Boc-L-histidine;Boc-His-OH;N-α-t.-Boc-L-histidine

CAS NO.：17791-52-5

Empirical Formula: C11H17N3O4

Molecular Weight: 255.27

MDL number: MFCD00065576

EINECS: 241-768-9

PRODUCT Properties

• Melting point: 195 °C (dec.)(lit.)
• alpha: 25.5 º (C=1, MEOH 25 ºC)
• Boiling point: 398.5°C (rough estimate)
• Density: 1.2235 (rough estimate)
• refractive index: 26 ° (C=1, MeOH)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMSO (Slightly), Methanol (Sparingly, Heated)
• pka: 3.56±0.10(Predicted)
• form: Powder, Crystals and/or Chunks
• color: White to off-white
• optical activity: [α]20/D +26°, c = 1 in methanol
• BRN: 755289
• Major Application: peptide synthesis
• InChI: InChI=1S/C11H17N3O4/c1-11(2,3)18-10(17)14-8(9(15)16)4-7-5-12-6-13-7/h5-6,8H,4H2,1-3H3,(H,12,13)(H,14,17)(H,15,16)/t8-/m0/s1
• InChIKey: AYMLQYFMYHISQO-QMMMGPOBSA-N
• SMILES: C(O)(=O)[C@H](CC1N=CNC=1)NC(OC(C)(C)C)=O
• CAS DataBase Reference: 17791-52-5(CAS DataBase Reference)

Description and Uses

Nα-Boc-L-histidine is an N-Boc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• HS Code: 29339900
• Storage Class: 11 - Combustible Solids