A1282612
BIS-TRIS , For cell and insect cell culture, ≥98%(HPLC) , 6976-37-0
Synonym(s):
[ bis(2-Hydroxyethyl)imino]- tris(hydroxymethyl)methane;[bis(2-Hydroxyethyl)imino]-tris(hydroxymethyl)methane;2,2-Bis(hydroxyethyl)-(iminotris)- (hydroxymethyl)-methane;2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol;2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol
CAS NO.：6976-37-0
Empirical Formula: C8H19NO5
Molecular Weight: 209.24
MDL number: MFCD00002853
EINECS: 230-237-7
| Pack Size | Price | Stock | Quantity |
| 25G | RMB55.20 | In Stock |
|
| 100G | RMB211.20 | In Stock |
|
| 500G | RMB903.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 104 °C(lit.) |
| Boiling point: | 466.2±40.0 °C(Predicted) |
| Density | 1.346±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Solution |
| color | Yellow to orange |
| Odor | Odorless |
| PH | 9.0-10.1 (20-25℃, 1M in water) |
| PH Range | 5.8 - 7.2 |
| pka | 6.5(at 25℃) |
| biological source | synthetic |
| Water Solubility | soluble |
| λmax | λ: 280 nm Amax: 0.15 |
| Sensitive | Air Sensitive |
| BRN | 2205275 |
| Major Application | diagnostic assay manufacturing |
| Cosmetics Ingredients Functions | BUFFERING |
| InChI | 1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2 |
| InChIKey | OWMVSZAMULFTJU-UHFFFAOYSA-N |
| SMILES | OCCN(CCO)C(CO)(CO)CO |
| LogP | -2.26 at 20℃ |
| CAS DataBase Reference | 6976-37-0(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)- (6976-37-0) |
| Absorption | cut-off at 270nm in H2O at 1M |
Description and Uses
Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological-based formulations.
Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338+P310 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-21/22-20/21/22 |
| Safety Statements | 26-36-36/37/39-22 |
| WGK Germany | 3 |
| F | 10-23 |
| TSCA | TSCA listed |
| HS Code | 29221980 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 |
| REACH Registrations | Active |
